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Karen-Lise Garm Spindler
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    Introduction

    Dr. Karen-Lise Garm Spindler is a renowned Clinical Professor and Senior Consultant at the Department of Oncology, Aarhus University Hospital, Denmark. She has extensive experience in gastrointestinal cancer care and is recognized for her expertise in integrating cutting-edge research into clinical practice. Dr. Spindler focuses on colorectal and anal cancers, emphasizing personalized treatment approaches and advanced diagnostic techniques such as liquid biopsies and circulating tumor DNA (ctDNA).

    • Full Name: Dr. Karen-Lise Garm Spindler
    • Title: MD, Clinical Professor, Senior Consultant
    • Years of Experience: Over 20 years in oncology and gastrointestinal cancer research
    • Main Focus: Gastrointestinal cancers, particularly colorectal and anal cancers; research in ctDNA and liquid biopsies

    Educational Background

    Dr. Spindler has an extensive academic foundation that underpins her clinical and research expertise. She completed her medical degree in Denmark and pursued advanced doctoral studies to become a leading expert in gastrointestinal oncology.

    • Medical School: Aarhus University, Denmark, MD
    • Doctor of Medical Science (DMSc): Aarhus University; specialized in colorectal cancer research
    • Doctoral Dissertation: “Clinical utility of tumor-specific mutations and circulating nucleic acids in plasma from patients with metastatic colorectal cancer” (2019)
    • Fellowships: Received a DKK 5 million fellowship from the Novo Nordisk Foundation for translational research bridging clinical and basic biomedical studies
    Read more

    Professional Experience

    Dr. Spindler combines clinical practice with leadership in research networks and teaching. Her professional experience highlights her commitment to improving cancer treatment outcomes through evidence-based practice.

    • Current Position: Professor and Senior Consultant, Department of Oncology, Aarhus University Hospital
    • Clinical Leadership: Supervises PhD students, medical students, research assistants, and postdoctoral researchers
    • Research Leadership: Leads the Danish Anal Cancer Group (DACG) and international IMACC consortium
    • Previous Roles: Former Chair of the Scientific Committee, Danish Cancer Society (KBVU)

    Academic Contributions

    Dr. Spindler is actively involved in teaching, mentoring, and research, bridging the gap between clinical practice and innovative oncology studies.

    • Teaching: Supervises students and postdoctoral researchers in oncology and clinical research
    • Research Interests: Clinical application of ctDNA, liquid biopsies, gastrointestinal cancer biomarkers
    • Conference Participation: Keynote speaker and contributor at international oncology meetings
    • Course Development: Develops programs to educate healthcare professionals on oncology advances

    Areas of Expertise

    Dr. Spindler specializes in complex gastrointestinal cancers and the use of molecular diagnostics to personalize treatment strategies.

    • Gastrointestinal Cancers: Colorectal and anal cancers, with focus on individualized treatment
    • Liquid Biopsies and ctDNA: Monitoring treatment response, early detection of recurrence
    • Radiotherapy Integration: Combines radiotherapy with targeted therapeutic strategies
    • Biomarker Development: Identifies and validates molecular markers for therapy selection

    Publications and Research

    Dr. Spindler has an extensive publication record in peer-reviewed journals, demonstrating her contribution to advancing cancer care:

    • “Total cell-free DNA measurement in metastatic colorectal cancer patients”: Examines ctDNA as a biomarker for treatment monitoring (2022)
    • “One-year treatment-related side effects and quality of life in rectal cancer patients”: Studies long-term patient outcomes post-treatment (2023)
    • “Biological features of squamous cell carcinoma of the anus: a deep dive review”: Reviews pathophysiology and clinical management of anal cancer (2025)
    • Research Profiles: Extensive research available through institutional repositories and ORCID profiles

    Patient Care Philosophy

    Dr. Spindler emphasizes compassionate, evidence-based care, prioritizing patient education, empathy, and collaborative decision-making. She ensures patients understand their treatment options and encourages active participation in the care process.

    • Communication: Provides clear explanations of diagnoses and treatment plans
    • Patient Education: Empowers patients with knowledge about disease and therapy options
    • International Patients: Offers care to patients worldwide and supports online pre-consultations
    • Compassionate Approach: Focuses on culturally sensitive care and high patient satisfaction

    Professional Affiliations

    • Danish Cancer Society (KBVU): Former Chair of the Scientific Committee
    • Danish Anal Cancer Group (DACG): Leadership in clinical trials and research initiatives
    • IMACC Consortium: Leads international collaboration on anal cancer and ctDNA studies
    • Clinical Research Networks: Active participant in national ctDNA-RECIST network

    FAQs

    Is Dr. Karen-Lise Garm Spindler board-certified?
    Yes, she is board-certified in oncology and holds a Doctor of Medical Science degree.
    What types of surgeries does she perform?
    Dr. Spindler specializes in gastrointestinal cancer surgeries, particularly colorectal and anal cancer procedures.
    Does she treat international patients?
    Yes, she provides care for international patients and offers online pre-consultations.
    How long is the typical hospital stay?
    The duration depends on the procedure and treatment plan, with personalized care provided for each patient.
    What languages does she speak?
    She is fluent in Danish and English, facilitating communication with international patients.
    What is her approach to patient care?
    Dr. Spindler emphasizes empathy, clear communication, patient education, and shared decision-making.
    What are her main research interests?
    Her research focuses on ctDNA, liquid biopsies, biomarkers, and improving treatment strategies for gastrointestinal cancers.

    Certification & Accreditation

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    Karen-Lise Garm SpindlerDenmark, Aarhus
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